AIDS-Related Lymphoma

Lymphoma is a type of blood tumor commonly present in human immunodeficiency virus (HIV)-infected individuals. In addition to an ineffective immune system caused by HIV, researchers discovered multiple factors contributing to the disease, including changes in human genetic information, invasion of other viruses, and slow activation of immune cells. Such various causes generated many subsequent branches of AIDS-Related Lymphoma.

Some common basic symptoms include fever, night sweats, and weight loss. However, there are more specific symptoms for various sub-branches of lymphoma. Specifically, when lymphoma reaches the brain, damaging the central nervous system, patients will experience headaches, nausea, vomiting, papilledema, and local compression symptoms such as epilepsy, memory loss, unstable gait, visual impairment, and blurred speech.

Unfortunately, most techniques discovered by researchers are somehow toxic to body cells and some types of lymphoma resist such treatments. As a result, it is necessary to maintain a good balance between the patient’s well-being and treatment effects. The main focus shifts to measures for the prevention of such diseases, such as emphasizing personal health and reducing the risk of getting infected.

References:

Berhan A, Bayleyegn B, Getaneh Z. HIV/AIDS Associated Lymphoma: Review. Blood Lymphat Cancer. 2022 Apr 29;12:31-45. doi: 10.2147/BLCTT.S361320. PMID: 35517869; PMCID: PMC9063794.

Mwamba PM, Mwanda WO, Busakhala NW, Strother RM, Loehrer PJ, Remick SC. AIDS-related non-Hodgkin’s lymphoma in sub-Saharan Africa: current status and realities of therapeutic approach. Lymphoma. 2012;2012:1–9.

Zhao H, Ma M, Zhang L, et al. Diagnosis of central nervous system lymphoma via cerebrospinal fluid cytology: a case report. BMC Neurol. 2019;19(1):1–6

Narkhede M, Arora S, Ujjani C. Primary effusion lymphoma: current perspectives. Onco Targets Ther. 2018;11:3747.

Re A, Cattaneo C, Rossi G. HIV and lymphoma: from epidemiology to clinical management. Mediterr J Hematol Infect Dis. 2019;11(1)